The Texas Regional Collaboratives for Excellence in Science Teaching were formed to improve the academic achievement of students in science through teacher professional development. Each Regional Collaborative across the state is led by a Project Director and Instructional Team Members that provide direct professional development to teachers of science.

• Region 1 Collaborative / Edinburg
• UT-Brownsville Regional Collaborative / Brownsville
• UT-Pan American Regional Collaborative / Edinburg
• TAMIU Regional Collaborative / Laredo
• TAMU-Corpus Christi / ESC 2 Regional Collaborative / Corpus Christi
• Region 3 Collaborative / Victoria
• Region 4 Collaborative / Houston
• Lake Houston Regional Collaborative / Humble
• Rice University Regional Collaborative / Houston
• UH-Clear Lake Regional Collaborative / Houston
• Aldine Collaborative / Houston
• Galveston County Regional Collaborative / Galveston
• Region 5 Collaborative / Beaumont
• TAMU-College Station Regional Collaborative /
  College Station
• Region 7 Collaborative / Kilgore
• Region 8 Collaborative / Mount Pleasant
• TAMU-Texarkana Regional Collaborative / Texarkana
• Region 9 Collaborative / Wichita Falls
• Region 10 Collaborative / Richardson
• UT-Dallas Regional Collaborative / Dallas
• Region 11 Collaborative / Fort Worth
• University of North Texas Regional Collaborative / Denton
• North Central Texas College Regional Collaborative / Gainesville
• Region 12 Collaborative / Waco
• Region 13 Collaborative / Austin
• Capital City Regional Collaborative / Austin
• ACC Regional Collaborative / Austin
• Region 14 Collaborative / Abilene
• Region 15 Collaborative / San Angelo
• Region 16 Collaborative / Amarillo
• Region 17 Collaborative / Lubbock
• Region 18 Collaborative / Midland
• Region 19 Collaborative / El Paso
• Region 20 Collaborative / San Antonio
• OLLU Regional Collaborative / San Antonio
• UT Tyler Collaborative
• UTSA Collaborative / San Antonio
• UT-M.D. Anderson Collaborative / Smithville